Melioidosis Cohort and Controls

In-patients at Sappasitthiprasong Hospital, Ubon Ratchathani over 18 years of age with melioidosis were recruited (Melioid Cohort) following positive culture of B. pseudomallei from a clinical specimen, alongside healthy control subjects attending the hospital’s blood donation clinic (Healthy Control Cohort) and subjects attending the hospital’s diabetes outpatient clinic (Diabetes Control Cohort). For patients who did not attend follow-up, their 28 day survival status was determined by using the hospital mortality records and by telephone.

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Jenjaroen K., Chumseng S., Sumonwiriya M., Ariyaprasert P., Chantratita N., Sunyakumthorn P., Hongsuwan M., Wuthiekanun V., Fletcher H.A., Teparrukkul P., Limmathurotsakul D., Day N.P, & Dunachie S.J. (2015). T-Cell Responses Are Associated with Survival in Acute Melioidosis Patients. PLoS Neglected Tropical Diseases, 9(10), e0004152.

Publication 2015

Blood donation Diabetes Healthy subjects In hospital patients Melioidosis Patients

Corresponding Organization : University of Oxford

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Protocol cited in 9 other protocols

Variable analysis

independent variables

Melioid Cohort (in-patients at Sappasitthiprasong Hospital, Ubon Ratchathani over 18 years of age with melioidosis)
Healthy Control Cohort (healthy control subjects attending the hospital's blood donation clinic)
Diabetes Control Cohort (subjects attending the hospital's diabetes outpatient clinic)

dependent variables

28 day survival status

control variables

Patients who did not attend follow-up

controls

Positive control: Melioid Cohort (in-patients at Sappasitthiprasong Hospital, Ubon Ratchathani over 18 years of age with melioidosis)
Negative controls: Healthy Control Cohort (healthy control subjects attending the hospital's blood donation clinic) and Diabetes Control Cohort (subjects attending the hospital's diabetes outpatient clinic)

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