Comprehensive UK Biobank Cohort Study

UK Biobank is a prospective cohort study with over 500,000 individuals with an age range of 38 to 73 years at recruitment between 2006 and 2010 from 22 study centers in England, Scotland, and Wales. Data on anthropometry, lifestyle, health-related indicators, and biological samples were collected (42 , 43 (link)). Up to 488,377 individuals were genotyped using either a custom Affymetrix UK Biobank Axiom Array chip or a custom Affymetrix UK BiLEVE Axiom Array chip (43 (link)).

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Peruchet-Noray L., Sedlmeier A.M., Dimou N., Baurecht H., Fervers B., Fontvieille E., Konzok J., Tsilidis K.K., Christakoudi S., Jansana A., Cordova R., Bohmann P., Stein M.J., Weber A., Bézieau S., Brenner H., Chan A.T., Cheng I., Figueiredo J.C., Garcia-Etxebarria K., Moreno V., Newton C.C., Schmit S.L., Song M., Ulrich C.M., Ferrari P., Viallon V., Carreras-Torres R., Gunter M.J, & Freisling H. (2024). Tissue-specific genetic variation suggests distinct molecular pathways between body shape phenotypes and colorectal cancer. Science Advances, 10(16), eadj1987.

Publication 2024

UK BiLEVE Axiom Array chip

Corresponding Organization : Institut d'Investigació Biomèdica de Girona

Other organizations : Universitat de Barcelona, University Hospital Regensburg, University of Regensburg, Centre Léon Bérard, University of Ioannina, King's College London, University of Vienna, Centre Hospitalier Universitaire de Nantes, German Cancer Research Center, National Center for Tumor Diseases, Massachusetts General Hospital, Harvard University, University of California, San Francisco, Cedars-Sinai Medical Center, Biogipuzkoa Health Research Institute, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Institut Català d'Oncologia, Institut d'Investigació Biomédica de Bellvitge, Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública, American Cancer Society, Cleveland Clinic, Huntsman Cancer Institute, University of Utah

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Variable analysis

independent variables

None explicitly mentioned

dependent variables

Anthropometry
Lifestyle
Health-related indicators
Biological samples

control variables

None explicitly mentioned

controls

No positive or negative controls mentioned

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