Serum IgE and Cytokine Levels

Total serum and allergen-specific serum IgE levels were examined based on a previous study.15 (link) Total serum IgE level was measured by ImmunoCAP (Phadia), and specific IgE levels to food (egg protein, milk, peanut, soybean, wheat, buckwheat, cashew nut, pistachio nuts, filbert, beef, mutton, shrimp, crab, peach, apple, mango, and strawberry) and inhalant (Dermatophagoides pteronyssinus and Dermatophagoides farinae) allergens were determined using a commercial assay for IgE (ImmunoCAP Phadiatop Infant; Phadia). Serum cytokine IL-4 level was measured according to the manufacturer’s instructions.

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Zou X.L., Wu J.J., Ye H.X., Feng D.Y., Meng P., Yang H.L., Wu W.B., Li H.T., He Z, & Zhang T.T. (2021). Associations Between Gut Microbiota and Asthma Endotypes: A Cross-Sectional Study in South China Based on Patients with Newly Diagnosed Asthma. Journal of Asthma and Allergy, 14, 981-992.

Publication 2021

ImmunoCAP ImmunoCAP Phadiatop Infant

Allergens Assay Beef Buckwheat Cashew nut Crab Cytokine Dermatophagoides farinae Dermatophagoides pteronyssinus Egg protein Filbert Food Infant Inhalant Mango Milk Peach Peanut Pistachio nuts Serum Soybean Strawberry Wheat

Corresponding Organization : Sun Yat-sen University

Other organizations : Sixth Affiliated Hospital of Sun Yat-sen University

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Variable analysis

independent variables

Total serum IgE level
Allergen-specific serum IgE levels to food (egg protein, milk, peanut, soybean, wheat, buckwheat, cashew nut, pistachio nuts, filbert, beef, mutton, shrimp, crab, peach, apple, mango, and strawberry) and inhalant (Dermatophagoides pteronyssinus and Dermatophagoides farinae) allergens
Serum cytokine IL-4 level

dependent variables

Total serum IgE level
Allergen-specific serum IgE levels to food (egg protein, milk, peanut, soybean, wheat, buckwheat, cashew nut, pistachio nuts, filbert, beef, mutton, shrimp, crab, peach, apple, mango, and strawberry) and inhalant (Dermatophagoides pteronyssinus and Dermatophagoides farinae) allergens
Serum cytokine IL-4 level

control variables

Not explicitly mentioned

Annotations

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