Potentiometric Ion Sensor Integration

The printed circuit board was designed and wired by using the AutoCAD designer, and it was printed and aligned for soldering. After connecting the electrodes through the sensor interface, the board was powered by a battery module to collect potentiometric signals from the surface of the ion-sensing microneedle electrode. The signals were processed through a two-stage differential circuit to reduce signal distortion and common-mode noise interference. Subsequently, the collected analog signal was converted into a digital signal using the STM32 chip through analog-to-digital conversion, and a gradient conversion was performed according to the calibration curve obtained from in vitro experiments to obtain the corresponding ion concentration. The concentration was transmitted to the Bluetooth module via a serial port to send the concentration data of different ions to the mobile terminal that displays the trend graph of ion changes through the interface that was designed using LabVIEW software (NI, USA).

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Huang X., Zheng S., Liang B., He M., Wu F., Yang J., Chen H.J, & Xie X. (2023). 3D-assembled microneedle ion sensor-based wearable system for the transdermal monitoring of physiological ion fluctuations. Microsystems & Nanoengineering, 9, 25.

Publication 2023

LabVIEW software

Chip Potentiometric

Corresponding Organization :

Other organizations : Sun Yat-sen University

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Variable analysis

independent variables

Sensor interface design
Powering the board with a battery module

dependent variables

Potentiometric signals from the surface of the ion-sensing microneedle electrode
Analog signal converted to digital signal
Ion concentration calculated from calibration curve
Ion concentration data transmitted to mobile terminal

control variables

Printed circuit board design and wiring using AutoCAD
Alignment of the printed circuit board for soldering
Two-stage differential circuit to reduce signal distortion and common-mode noise interference
STM32 chip used for analog-to-digital conversion
Gradient conversion based on calibration curve from in vitro experiments
Bluetooth module for data transmission
LabVIEW software for mobile terminal interface

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