Controlled Ovarian Hyperstimulation Protocols

Women underwent controlled ovarian hyperstimulation with a GnRH antagonist protocol in the majority of the cases (Merck Serono, Geneve, Switzerland; Organon, Oss, Netherlands) and with an agonist protocol in the remaining cases (Sanofi Aventis, Frankfurt, Germany). For stimulation, recombinant follicle stimulating hormone (rFSH) was used in most cases (Organon; Merck Serono), while human menopausal gonadotropin (HMG) was used as an alternative (Ferring, Kiel, Germany). Ovulation trigger was performed either with human chorionic gonadotropin (Organon) or recombinant HCG (Merck-Serono). Estradiol serum levels were analyzed on the day of HCG or one day before (Pinto et al., 2009 (link)).

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Barros P., Cunha M., Barros A., Sousa M, & Dória S. (2022). Clinical outcomes of 77 TESE treatment cycles in non-mosaic Klinefelter syndrome patients. JBRA Assisted Reproduction, 26(3), 412-421.

Publication 2022

human menopausal gonadotropin (HMG) recombinant HCG

Estradiol Follicle stimulating hormone Gnrh Human chorionic gonadotropin Human menopausal gonadotropin Ovarian hyperstimulation Ovulation Serum Trigger Women

Corresponding Organization : Universidade do Porto

Other organizations : Centro de Genética Clínica, i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto

Top 5 similar protocols

Variable analysis

independent variables

Controlled ovarian hyperstimulation protocol (GnRH antagonist protocol or GnRH agonist protocol)
Stimulation medication (recombinant follicle stimulating hormone (rFSH) or human menopausal gonadotropin (HMG))
Ovulation trigger (human chorionic gonadotropin (HCG) or recombinant HCG)

dependent variables

Estradiol serum levels

control variables

Not explicitly mentioned

controls

Positive control: Not specified
Negative control: Not specified

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