Gadovist-enhanced MRI Sequence Analysis

Of the sequences obtained during standard-of-care MRI, we analyzed T2 fluid-attenuated inversion recovery (FLAIR) sequences obtained after administration of a 0.1 mmol/kg gadobutrol (Gadovist; Bayer Healthcare) with the following image parameters: 4 mm slice thickness, no gap, 10 000 ms repetition time, 106 ms echo time, 2600 ms inversion time, and 130° flip angle. Images were obtained by using either 1.5-T (Avanto, Siemens Medical Solutions) or 3-T (Skyra or Prisma, Siemens Medical Solutions) MR systems.

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Kim E.Y., Vavere A.L., Snyder S.E., Chiang J., Li Y., Patni T., Qaddoumi I., Merchant T.E., Robinson G.W., Holtrop J.L., Shulkin B.L, & Bag A.K. (2024). [11C]-methionine positron emission tomography in the evaluation of pediatric low-grade gliomas. Neuro-Oncology Advances, 6(1), vdae056.

Publication 2024

Gadovist Prisma

Corresponding Organization : St. Jude Children's Research Hospital

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Variable analysis

independent variables

Gadobutrol (Gadovist; Bayer Healthcare) administration

dependent variables

T2 fluid-attenuated inversion recovery (FLAIR) sequences

control variables

4 mm slice thickness
No gap
10 000 ms repetition time
106 ms echo time
2600 ms inversion time
130° flip angle
1.5-T (Avanto, Siemens Medical Solutions) or 3-T (Skyra or Prisma, Siemens Medical Solutions) MR systems

controls

No positive or negative controls were explicitly mentioned in the provided information.

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