The typical immunosuppressive regimen at our institute was described previously.[9 (link)] All kidney recipients receive basiliximab (Simulect, Novartis Pharmaceuticals Co., Basel, Switzerland) 20 mg on POD0 and 4 or antithymocyte globulin (ATG) (Thymoglobulin, Sanofi Genzyme, Cambridge, MA) 1.25 mg/kg from POD0 to 4 as induction immunosuppressants (in case of highly sensitized patients or expanded criteria deceased donor). Maintenance immunosuppression consists of tacrolimus (Tacrobell, Chong Kun Dang Pharmaceuticals Co., Seoul, Korea; Prograf, Astellas Pharma Inc., Toyama, Japan), corticosteroid, and either mycophenolate mofetil (Cellcept, Hoffmann-La Roche Inc., Nutley, NJ) or mycophenolate sodium (Myfortic, Novartis Pharmaceuticals Co.).
Protocol detail
Kidney Transplant Immunosuppressive Regimen
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Antithymocyte globulin
Basiliximab
Cellcept
Corticosteroid
Donor
Immunosuppressants
Immunosuppression
Kidney
Mycophenolate mofetil
Mycophenolate sodium
Myfortic
Patients
Pharmaceuticals
Prograf
Regimen
Simulect
Tacrolimus
Thymoglobulin
Corresponding Organization :
Other organizations : Catholic University of Korea, Bioscience Research, Uijeongbu St. Mary's Hospital
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Variable analysis
independent variables
- Basiliximab (Simulect, Novartis Pharmaceuticals Co., Basel, Switzerland) 20 mg on POD0 and 4
- Antithymocyte globulin (ATG) (Thymoglobulin, Sanofi Genzyme, Cambridge, MA) 1.25 mg/kg from POD0 to 4
- Tacrolimus (Tacrobell, Chong Kun Dang Pharmaceuticals Co., Seoul, Korea; Prograf, Astellas Pharma Inc., Toyama, Japan)
- Corticosteroid
- Mycophenolate mofetil (Cellcept, Hoffmann-La Roche Inc., Nutley, NJ) or mycophenolate sodium (Myfortic, Novartis Pharmaceuticals Co.)
- Not explicitly mentioned
- Not explicitly mentioned
- Positive control: Not mentioned
- Negative control: Not mentioned
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