Oral C. rodentium Infection in Mice

8–10-wk-old age- and gender-matched mice were orally administered 2 × 10⁹C. rodentium, strain DBS100 (ATCC), as previously described (Cella et al., 2009 (link)). Body weight of mice was measured until day 7. For Rapa injection, mice were injected i.p. with 200 µl of Rapa (5 mg/kg body weight) or DMSO vehicle before infection.

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Di Luccia B., Gilfillan S., Cella M., Colonna M, & Huang S.C. (2019). ILC3s integrate glycolysis and mitochondrial production of reactive oxygen species to fulfill activation demands. The Journal of Experimental Medicine, 216(10), 2231-2241.

Publication 2019

DBS100

Body weight Dmso Infection Mice Strain

Corresponding Organization : University School

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Variable analysis

independent variables

Rapamycin (Rapa) injection

dependent variables

Body weight of mice

control variables

8-10-week-old age- and gender-matched mice
Oral administration of 2 × 10^9 C. rodentium, strain DBS100 (ATCC)

controls

Positive control: Mice infected with C. rodentium and injected with Rapamycin (Rapa)
Negative control: Mice infected with C. rodentium and injected with DMSO vehicle

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