Of 31 participants who enrolled, two were found ineligible after starting treatment and were removed from the trial. The 29 eligible participants (15 women) had a mean age of 33.4 (SD = 11.2; range = 18 to 68), and a mean Y-BOCS score of 25.6 (SD = 4.8). Twelve patients had concurrent DSM-IV comorbid conditions including major depression (n = 7), generalized anxiety disorder (n = 4), social phobia (n = 3), specific phobia (n = 2), body dysmorphic disorder (n = 1), and dysthymia (n = 1). Fourteen patients were taking psychotropic medication: clonazepam (n = 4), fluvoxamine (n = 3), citalopram (n = 2), escitalopram (n = 2), paroxetine (n = 2), sertraline (n = 2), alprazolam (n = 1), buproprion (n = 1), clomipramine (n = 1), fluoxetine (n = 1), and venlafaxine (n = 1).
OCD Treatment Efficacy Trial
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Corresponding Organization :
Other organizations : Massachusetts General Hospital, Harvard University, University of Virginia
Protocol cited in 4 other protocols
Variable analysis
- None explicitly mentioned
- Yale-Brown Obsessive-Compulsive scale scores
- Participants were age 18 or older
- Participants met American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (4th ed.) criteria for a primary diagnosis of OCD
- Participants had Yale-Brown Obsessive-Compulsive scale scores of >16
- Individuals with primary hoarding were not admitted into the study
- Individuals were ineligible if they reported current suicidal or psychotic symptoms or other features necessitating psychiatric hospitalization, Tourette's Disorder, or showed evidence of mental retardation, dementia, brain damage, or other severe cognitive dysfunction
- Individuals were ineligible if they were currently engaged in psychotherapy, had previously received CT for OCD, or had been unsuccessfully treated with an adequate trial (10 or more sessions) of BT
- Individuals receiving psychopharmacological treatment could participate if they had been stably on or off medication for at least 2 months preceding study enrollment and remained stable throughout the trial
- None specified
- None specified
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