A detailed description of the complete imaging procedures of the ABCD study is described by Casey et al. [47 (link)]. The scanning protocol was designed to be implemented with three different 3T Scanners (Siemens, General Electric, and Philips), allowing for data harmonization across 21 different imaging sites.
For the current study, we used the structural MRI data acquired from 3D T1-weighted images with a 1 mm isotropic resolution. The 3D T1-weighted images were acquired while the participant watched a child-friendly movie. Centralized processing and analyses of MRI data were conducted by the ABCD Data Analysis and Informatics Center. Real-time motion detection and correction were utilized on General Electric and Siemens Scanners. Signal-to-Noise Ratio and head motion statistics were automatically calculated for quality control. For manual quality control, images were reviewed by trained technicians, and those deemed unacceptable due to artifacts were not included in the data set [48 (link)].
Cortical volumes were constructed using FreeSurfer version 5.3.0 and segmented according to the Desikan–Killiany atlas [49 (link)]. Total Cortical Volumes for the prefrontal cortex (our primary region of interest) and occipital cortex (a control region) were calculated by summing the volumes of the regions of interest included in these areas. We also used bilateral total cortical volume.
For the current study, we used the structural MRI data acquired from 3D T1-weighted images with a 1 mm isotropic resolution. The 3D T1-weighted images were acquired while the participant watched a child-friendly movie. Centralized processing and analyses of MRI data were conducted by the ABCD Data Analysis and Informatics Center. Real-time motion detection and correction were utilized on General Electric and Siemens Scanners. Signal-to-Noise Ratio and head motion statistics were automatically calculated for quality control. For manual quality control, images were reviewed by trained technicians, and those deemed unacceptable due to artifacts were not included in the data set [48 (link)].
Cortical volumes were constructed using FreeSurfer version 5.3.0 and segmented according to the Desikan–Killiany atlas [49 (link)]. Total Cortical Volumes for the prefrontal cortex (our primary region of interest) and occipital cortex (a control region) were calculated by summing the volumes of the regions of interest included in these areas. We also used bilateral total cortical volume.
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