The following locations were investigated in this study: IL-1β –31 T/C (rs1143643), IL-6 –174 G/C (rs1800795), TNF-α –308 G/A (rs1800629), and IFN-γ +874 A/T (rs2430561) genes. Genotyping was performed with TaqMan® 5’ nuclease allelic discrimination (Assay by Design/Demand, Applied Biosystems, Foster City, CA) as described previously [43 (link)–45 (link)].