The VVR score was calculated at 1 h, 24 h, and 48 h after surgery, as follows: VIS + ventilation index (VI) + renal score (change in serum creatinine from baseline × 10).
VIS was calculated using the following equation:
Dopamine dose (μg/kg/min) + Dobutamine dose (μg/kg/min) + 100 × Epinephrine dose (μg/kg/min) + 10 × Milrinone dose (μg/kg/min) + 10,000 × Vasopressin dose (μg/kg/min) + 100 × Norepinephrine dose (μg/kg/min) (7 (link)).
VI was calculated using the following formula:
VI = respiratory rate (RR) × (PIP − PEEP) × PaCO2/1,000; ΔCr was calculated by subtracting serum creatinine (in mg/dL) at the time of each measurement from the preoperative serum creatinine and VVR using the following formula:
VVR = VIS + VI + (ΔCr × 10) (8 (link)).
For patients whose postoperative serum creatinine values were less than preoperative values, ΔCr was taken as 0. For patients not requiring ventilator support at the time of measurement, VI was taken as 0.
VIS was calculated using the following equation:
Dopamine dose (μg/kg/min) + Dobutamine dose (μg/kg/min) + 100 × Epinephrine dose (μg/kg/min) + 10 × Milrinone dose (μg/kg/min) + 10,000 × Vasopressin dose (μg/kg/min) + 100 × Norepinephrine dose (μg/kg/min) (7 (link)).
VI was calculated using the following formula:
VI = respiratory rate (RR) × (PIP − PEEP) × PaCO2/1,000; ΔCr was calculated by subtracting serum creatinine (in mg/dL) at the time of each measurement from the preoperative serum creatinine and VVR using the following formula:
VVR = VIS + VI + (ΔCr × 10) (8 (link)).
For patients whose postoperative serum creatinine values were less than preoperative values, ΔCr was taken as 0. For patients not requiring ventilator support at the time of measurement, VI was taken as 0.
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