Retinal Veiling Luminance Reduction Protocol

Integration of the straylight parameter over an angular range was used to calculate the potential reduction in retinal veiling luminance (RVL)19 (link) with ZXR00V versus ZXR00. Under challenging light conditions, such as night driving with low road luminance and an oncoming car with intense headlights, the relative contrast enhancement was calculated for the scenario of a pedestrian crossing the road, as would be predicted to be observed by a pseudophakic patient implanted with either the ZXR00V or ZXR00 IOLs. The contrast is defined as the difference of the luminance target (pedestrian, Lt) and background luminance (road, Lb) divided by sum of luminance background and RVL as per the following equation:

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$${\rm{contrast\,ratio={{Lt-Lb} \over {Lb+RVL}}}}$$
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Pedestrian luminance of 2 cd/m² and 5 cd/m² and road luminance ranging between 0.2 and 1 cd.m² were chosen as realistic values for challenging light conditions at night.20 (link)

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van der Mooren M., Alarcon A., Jenkins Sanchez M.D, & Chang D.H. (2023). Effect of Violet Light-Filtering and Manufacturing Improvements in an Extended Depth-of-Focus Intraocular Lens on Visual Performance. Clinical Ophthalmology (Auckland, N.Z.), 17, 701-709.

Publication 2023

Iols Light Patient Pedestrian Retinal

Corresponding Organization :

Other organizations : Johnson & Johnson (Netherlands), Empire Eye Physicians

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Variable analysis

independent variables

IOL type (ZXR00V or ZXR00)

dependent variables

Relative contrast enhancement
Retinal veiling luminance (RVL)

control variables

Pedestrian luminance (2 cd/m^2 and 5 cd/m^2)
Road luminance (0.2 to 1 cd/m^2)
Challenging light conditions (night driving with low road luminance and an oncoming car with intense headlights)

controls

Positive control: Not explicitly mentioned.
Negative control: Not explicitly mentioned.

Annotations

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