Posaconazole (Selleck Chemicals; S1257), voriconazole (Selleck Chemicals; S1442), vismodegib (GDC-0449; LC Laboratories), sonidegib (NVP-LDE225; LC Laboratories), and KAAD-cyclopamine (Calbiochem; 239804), SAG (Cayman Chemical; 11914) were dissolved in DMSO. Arsenic trioxide (Sigma) was formulated as previously described (16 (link)). 20(S)-hydroxycholesterol (Steraloids Inc; C6480-000), lathosterol (Sigma), desmosterol (Sigma), and cholesterol (Sigma) were prepared in ethanol.
For in vivo experiments, Posaconazole oral suspension (Noxafil, Merck) was obtained from the pharmacies of University of Texas Southwestern, Stanford Comprehensive Cancer Center or The Children’s Hospital and Research Center at Oakland and diluted as necessary with sterile water.
For in vivo experiments, Posaconazole oral suspension (Noxafil, Merck) was obtained from the pharmacies of University of Texas Southwestern, Stanford Comprehensive Cancer Center or The Children’s Hospital and Research Center at Oakland and diluted as necessary with sterile water.
