Aprepitant Nano-Formulation Development

Aprepitant (APT, purity ≥ 98.5%) was purchased from Zhongshan Yiantai Pharma Co. Ltd. (Guangzhou, China). Egg yolk lecithin and sodium oleate were purchased from Shanghai A.V.T. Pharma Co. Ltd. (Shanghai, China). Poloxamer 188 (F68), sucrose and medium-chain triglyceride (MCT) were purchased from Xi’an Tianzheng Medicinal Materials Co. Ltd. (Zhejiang, China). Ethanol was purchased from Shandong Long Yu Quan Pharmaceutical Excipients Co. Ltd. (Shandong, China). All chemicals and reagents were of analytical or HPLC grade.

Free full text: Click here

Li Y., Yin H., Wu C., He J., Wang C., Ren B., Wang H., Geng D., Zhang Y, & Zhao L. (2023). Preparation and in vivo evaluation of an intravenous emulsion loaded with an aprepitant-phospholipid complex. Drug Delivery, 30(1), 2183834.

Publication 2023

Aprepitant Egg yolk Ethanol Hplc Lecithin Pharmaceutical excipients Poloxamer 188 Sodium oleate Sucrose Triglyceride

Corresponding Organization : Tangshan College

Other organizations : Tangshan People's Hospital, Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine

Top 5 similar protocols

Variable analysis

independent variables

Aprepitant (APT, purity ≥ 98.5%)
Egg yolk lecithin
Sodium oleate
Poloxamer 188 (F68)
Sucrose
Medium-chain triglyceride (MCT)
Ethanol

dependent variables

Not explicitly mentioned

control variables

Not explicitly mentioned

positive controls

Not specified

negative controls

Not specified

Annotations

Based on most similar protocols

Etiam vel ipsum. Morbi facilisis vestibulum nisl. Praesent cursus laoreet felis. Integer adipiscing pretium orci. Nulla facilisi. Quisque posuere bibendum purus. Nulla quam mauris, cursus eget, convallis ac, molestie non, enim. Aliquam congue. Quisque sagittis nonummy sapien. Proin molestie sem vitae urna. Maecenas lorem.

As authors may omit details in methods from publication, our AI will look for missing critical information across the 5 most similar protocols.

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!