Participants were scanned pre-, mid-, and post-intervention. MR images were acquired using a 3T Magnetom Tim Trio MRI scanner system (Siemens Medical Systems, Erlangen) using a 32-channel radiofrequency head coil. T1-weighted images were obtained using a 3D T1-weighted magnetization prepared gradient-echo (MPRAGE) sequence. The multi-parameter mapping protocol used to acquire the MT maps comprised one static magnetic (B0) gradient echo (GRE)-field map, one radiofrequency (RF) transmit field map (B1), and three multi-echo 3D fast low angle shot (FLASH) scans (Helms et al., 2008b (link); Tabelow et al., 2019 (link)). Diffusion-weighted images were obtained with a single-shot diffusion-weighted spin-echo-refocused echo-planar imaging sequence. Further details regarding the acquisition parameters can be found in the Supplementary Material.
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