The neutralization panel data (IC50 and IC80 values for specific monoclonal antibodies and pseudotyped viruses) were collected from 49 published neutralization studies, mostly from tables in PDF format provided in the supplemental materials. The viral data was collected from Los Alamos HIV Database and in some cases personal communication with the authors, and required careful consideration and systematization to resolve sequence name ambiguities between different laboratories. Antibody sequences were downloaded from GenBank, and links to the structures in Protein Data Bank are provided. Standard statistics are applied to tally and analyze neutralization results. Specifically, antibody associations with viral mutations are evaluated by Fisher's exact test, counting the number of antibody-resistant or antibody-sensitive viruses (above or below threshold of detection) and the presence or absence of specific amino acids or N-glycosylation motif in the viral sequence alignment position (12 (link)).