Lung images were acquired using a computed tomography (CT) system (Vereos-Ingenuity, Philips) as previously described25 (link),26 (link). Lesions were defined as ground glass opacity, crazy-paving pattern, consolidation or pleural thickening as previously described32 ,48 . Lesions and scoring were assessed in each lung lobe blindly and independently by two persons and the final results were established by consensus. Overall CT scores include the lesion type (scored from 0 to 3) and lesion volume (scored from 0 to 4) summed for each lobe as previously described25 (link),26 (link).
Maisonnasse P., Aldon Y., Marc A., Marlin R., Dereuddre-Bosquet N., Kuzmina N., Freyn A., Snitselaar J., Gonçalves A., Caniels T., Burger J., Poniman M., Chesnais V., Diry S., Iershov A., Ronk A., Jangra S., Rathnasinghe R., Brouwer P., Bijl T., van Schooten J., Brinkkemper M., Liu H., Yuan M., Mire C., van Breemen M., Contreras V., Naninck T., Lemaître J., Kahlaoui N., Relouzat F., Chapon C., Ho Tsong Fang R., McDanal C., Osei-Twum M., St-Amant N., Gagnon L., Montefiori D., Wilson I., Ginoux E., de Bree G., García-Sastre A., Schotsaert M., Coughlan L., Bukreyev A., van der Werf S., Guedj J., Sanders R., van Gils M, & Le Grand R. (2021). COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models. Research Square.
Other organizations :
Inserm, CEA Paris-Saclay, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Université Paris-Saclay, Amsterdam University Medical Centers, Infectious Disease Models and Innovative Therapies, Icahn School of Medicine at Mount Sinai, Université Paris Cité, University of Amsterdam, Scripps Research Institute, The University of Texas Medical Branch at Galveston, Duke University, Exelis (United States), University of Maryland, Baltimore, Institut Pasteur
Lesion type (scored from 0 to 3) and lesion volume (scored from 0 to 4) in each lung lobe
control variables
Not explicitly mentioned
controls
Not specified
Not specified
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