Transgenic Mouse Models for Muscular Dystrophy

Emx1-Cre transgenic mice [33 (link)] were obtained from the Jackson Laboratories (Bar Harbor, ME, USA). POMT2-floxed mice have been reported [28 (link)]. These mice were purposely maintained on a 129SV and C57/B6 hybrid background to avoid artificial phenotypes that can be caused by homozygosity of inbred strains. Protocols for using laboratory mice were approved by the Institutional Committee for Use and Care of Laboratory Animals at State University of New York Upstate Medical University (CHUA#367) and adhered to the guidelines of the National Institutes of Health. All efforts were made to minimize pain and suffering of animals.