For quantification of IR, HOMA-IR was calculated as follows: HOMA-IR = fasting insulin (μU/dL) × fasting glucose (mg/dL) / 22.5. TyG index, TyG-WC, TyG-BMI were calculated using the formula published previously. The TyG index [17 (link),18 (link)]: Ln[TG (mg/ dL) × fasting glucose (mg/dL)/2]. TyG-BMI, TyG-WC and TyG-WHtR indicate TyG index x BMI [20 (link)], TyG index x WC [20 (link)] and TyG index x WHtR, respectively.
Metabolic Markers and Insulin Resistance
For quantification of IR, HOMA-IR was calculated as follows: HOMA-IR = fasting insulin (μU/dL) × fasting glucose (mg/dL) / 22.5. TyG index, TyG-WC, TyG-BMI were calculated using the formula published previously. The TyG index [17 (link),18 (link)]: Ln[TG (mg/ dL) × fasting glucose (mg/dL)/2]. TyG-BMI, TyG-WC and TyG-WHtR indicate TyG index x BMI [20 (link)], TyG index x WC [20 (link)] and TyG index x WHtR, respectively.
Corresponding Organization : Chungnam National University Hospital
Protocol cited in 7 other protocols
Variable analysis
- Fasting blood glucose
- Triglycerides
- Total cholesterol
- HDL-C
- Serum insulin
- HOMA-IR
- TyG index
- TyG-WC
- TyG-BMI
- 8-hour overnight fast
- Venous blood sample
- ADVIA 1650 chemistry analyzer (Siemens, Washington, DC, USA) used in 2007
- Hitachi 7600 automatic analyzer (Hitachi, Tokyo, Japan) used from 2008 to 2010
- HDL-C corrected values using KCDC conversion equations
- LDL-C calculated using Friedewald equation
- Serum insulin measured by 1470 Wizard gamma counter (Perkin-Elmer, Turku, Finland)
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