Sertraline (Pfizer Inc, CT, USA) was administered at a dose of 25 mg/kg i.p. 30 min prior to the forced-swim test. The FST was conducted as previously described [3 (link)]. Each session lasted for 300 s and was videorecorded. Unbiased analysis of total immobility time over the final 240 s was performed using the ForcedSwimScan (CleverSys Inc, VA, USA).
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Sertraline Effects on Forced Swim Test
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Corresponding Organization : Florey Institute of Neuroscience and Mental Health
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- Sertraline (Pfizer Inc, CT, USA) administered at a dose of 25 mg/kg i.p. 30 min prior to the forced-swim test
- Total immobility time over the final 240 s of the forced-swim test
- Forced-swim test conducted as previously described [3 (link)]
- Each session lasted for 300 s and was videorecorded
- Unbiased analysis of total immobility time over the final 240 s was performed using the ForcedSwimScan (CleverSys Inc, VA, USA)
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