Clinical outcomes from the initiation of eribulin treatment were assessed. The physician-reported real-world best overall response was abstracted from patient’s medical chart as recorded by the physician at the time of assessment and categorized as complete response (CR), partial response (PR), stable disease (SD), or progressive disease (PD). Real-world progression-free survival (rwPFS) was calculated from the date of eribulin initiation to the earliest date of physician-reported progression or death due to any cause while on eribulin treatment or within 90 days after eribulin treatment discontinuation, as long as no subsequent treatments had been initiated. Patients with no documented progression or death event were censored at 90 days after eribulin discontinuation, start of the new line of therapy, or at the last available follow-up in the medical record, whichever was earliest. Overall survival (OS) was calculated from the date of eribulin initiation to death due to any cause; if no death event occurred, patients were censored at the last available follow-up in the medical record.
Real-World Eribulin Treatment Outcomes
Clinical outcomes from the initiation of eribulin treatment were assessed. The physician-reported real-world best overall response was abstracted from patient’s medical chart as recorded by the physician at the time of assessment and categorized as complete response (CR), partial response (PR), stable disease (SD), or progressive disease (PD). Real-world progression-free survival (rwPFS) was calculated from the date of eribulin initiation to the earliest date of physician-reported progression or death due to any cause while on eribulin treatment or within 90 days after eribulin treatment discontinuation, as long as no subsequent treatments had been initiated. Patients with no documented progression or death event were censored at 90 days after eribulin discontinuation, start of the new line of therapy, or at the last available follow-up in the medical record, whichever was earliest. Overall survival (OS) was calculated from the date of eribulin initiation to death due to any cause; if no death event occurred, patients were censored at the last available follow-up in the medical record.
Corresponding Organization : University of Vermont
Other organizations : RTI Health Solutions, Eisai (United States)
Variable analysis
- Patient demographics
- Clinical characteristics
- Eribulin treatment characteristics
- Physician-reported real-world best overall response (CR, PR, SD, PD)
- Real-world progression-free survival (rwPFS)
- Overall survival (OS)
- Control variables not explicitly mentioned.
- No positive or negative controls specified.
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