M. tuberculosis laboratory strains H37Ra (ATCC 25177) and H37Rv (ATCC 27294) were used in the HFS-TB experiments. Culture conditions for stock bacterial strains and the human-derived THP-1 cells (ATCC TIB-202) were the same as reported in our previous publications.10–12 (link) Study drugs were purchased from Sigma−Aldrich (St Louis, MO, USA), Baylor Medical Center campus pharmacy and BOC Sciences (NY, USA). The mycobacterial growth indicator tube (MGIT) system and related supplies were purchased from Becton Dickinson (Franklin Lakes, NJ, USA).
Srivastava S., Deshpande D., Magombedze G., van Zyl J., Cirrincione K., Martin K., Bendet P., Berg A., Hanna D., Romero K., Hermann D, & Gumbo T. (2019). Duration of pretomanid/moxifloxacin/pyrazinamide therapy compared with standard therapy based on time-to-extinction mathematics. Journal of Antimicrobial Chemotherapy, 75(2), 392-399.
M. tuberculosis laboratory strains H37Ra (ATCC 25177) and H37Rv (ATCC 27294)
dependent variables
Measured outcomes (not explicitly mentioned)
control variables
Culture conditions for stock bacterial strains and the human-derived THP-1 cells (ATCC TIB-202)
Study drugs were purchased from Sigma−Aldrich (St Louis, MO, USA), Baylor Medical Center campus pharmacy and BOC Sciences (NY, USA)
The mycobacterial growth indicator tube (MGIT) system and related supplies were purchased from Becton Dickinson (Franklin Lakes, NJ, USA)
controls
Positive control: Not specified
Negative control: Not specified
Annotations
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