Longitudinal Multimodal Brain Imaging

MR images were acquired at two time points (2011 and 2015) on the same 1.5-Tesla Siemens Magnetom Avanto scanner and included the following whole brain scans: T1-weighted 3D MPRAGE imaging (isotropic voxel size 1.0 mm³), a FLAIR sequence (voxel size 0.5 × 0.5 × 2.5 mm; interslice gap 0.5 mm) and a DTI sequence (isotropic voxel size 2.5 mm³, 8 unweighted scans, 60 diffusion weighted scans at b = =900 s/mm²). Full acquisition details have been described previously (van Leijsen et al., 2017 (link); van Norden et al., 2011 (link)).

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van Leijsen E.M., van Uden I.W., Bergkamp M.I., van der Holst H.M., Norris D.G., Claassen J.A., Kessels R.P., de Leeuw F.E, & Tuladhar A.M. (2019). Longitudinal changes in rich club organization and cognition in cerebral small vessel disease. NeuroImage : Clinical, 24, 102048.

Publication 2019

Magnetom Avanto scanner

Brain Diffusion Scans

Corresponding Organization : Radboud University Nijmegen

Other organizations : Jeroen Bosch Ziekenhuis, Erwin L. Hahn Institute for Magnetic Resonance Imaging, University of Duisburg-Essen

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Variable analysis

independent variables

Time points (2011 and 2015)

dependent variables

MRI scans
T1-weighted 3D MPRAGE imaging
FLAIR sequence
DTI sequence

control variables

1.5-Tesla Siemens Magnetom Avanto scanner
Isotropic voxel size 1.0 mm^3 for T1-weighted 3D MPRAGE imaging
Voxel size 0.5 × 0.5 × 2.5 mm with 0.5 mm interslice gap for FLAIR sequence
Isotropic voxel size 2.5 mm^3 for DTI sequence
8 unweighted scans and 60 diffusion weighted scans at b = 900 s/mm^2 for DTI sequence

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