Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection in IBD Patients

All enrolled patients provided written informed consent prior to the FMT procedure and their clinical data and stool samples were collected. Eligible patients were adults (≥18 years) and required to have documentation of typical histopathology for IBD with colonic involvement and a confirmed diagnosis of at least three or more documented rCDI with typical laboratory findings. The study protocol conformed to the ethical guidelines of the Institutional Ethical Review Committee of the Research Institute for Gastroenterology and Liver Diseases at Shahid Beheshti University of Medical Sciences (Project No. IR.SBMU.RIGLD.REC.1398.036).

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Gholam-Mostafaei F.S., Azimirad M., Naseri K., Nabavi-Rad A., Asadzadeh Aghdaei H., Shahrokh S., Ebrahimi Daryani N., Yadegar A, & Zali M.R. (2023). Intestinal microbiota changes pre- and post-fecal microbiota transplantation for treatment of recurrent Clostridioides difficile infection among Iranian patients with concurrent inflammatory bowel disease. Frontiers in Microbiology, 14, 1147945.

Publication 2023

Adults Colonic Diagnosis Diseases of liver Ethical review Patients Stool

Corresponding Organization : Shahid Beheshti University of Medical Sciences

Other organizations : Tehran University of Medical Sciences

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independent variables

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dependent variables

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control variables

All enrolled patients provided written informed consent prior to the FMT procedure
Eligible patients were adults (≥18 years) and required to have documentation of typical histopathology for IBD with colonic involvement and a confirmed diagnosis of at least three or more documented rCDI with typical laboratory findings
The study protocol conformed to the ethical guidelines of the Institutional Ethical Review Committee of the Research Institute for Gastroenterology and Liver Diseases at Shahid Beheshti University of Medical Sciences (Project No. IR.SBMU.RIGLD.REC.1398.036)

positive controls

No positive controls are explicitly mentioned in the input protocol.

negative controls

No negative controls are explicitly mentioned in the input protocol.

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