Thyroid tissue samples were collected from surgeries from AITD patients at the Hospital Universitario de la Princesa and from non-thyroid pathology laryngectomy samples or healthy organ donors at the Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP-HUGTIP) Biobank. Clinical diagnoses were all reviewed by a single experienced endocrinologist based on standard clinical, laboratory, and histological criteria. Serum free thyroxine (FT4), thyroid-stimulating hormone (TSH), and antibodies against thyroglobulin (TG), thyroperoxidase (TPO), and TSH receptor (TSH-R) were determined in all patients at the time of the surgery. Clinical data are shown in Table 1 .
This study was approved by the Internal Ethical Review Committee of Hospital Universitario de la Princesa (Committee Register Number: 2796, approval date: 26 May 2016), and written informed consent was obtained from all patients in accordance with the Declaration of Helsinki.
This study was approved by the Internal Ethical Review Committee of Hospital Universitario de la Princesa (Committee Register Number: 2796, approval date: 26 May 2016), and written informed consent was obtained from all patients in accordance with the Declaration of Helsinki.
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