Catheter Deliverability of Bismuth Beads

Catheter deliverability of the bismuth beads through two clinical microcatheter sizes (2.0-Fr Progreat, Terumo, Somerset, NJ and 2.4 Fr Renegade, Boston Scientific Corp.) was evaluated by administering a homogenous bead suspension in 100% iohexol (Omnipaque 350, GE Healthcare, Waukesha, WI) as a 1:10 bead dilution and using 1- or 3-mL syringes^{10 (link)}. The catheters were laid on a bench with a 10 cm diameter coil mid-catheter to introduce curvature in the flow path. Any catheter clogging was recorded as a failure and denoted that bead size was not suitable to the respective catheter.

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Negussie A.H., de Ruiter Q.M., Britton H., Donahue D.R., Boffi Q., Kim Y.S., Pritchard W.F., Moonen C., Storm G., Lewis A.L, & Wood B.J. (2021). Synthesis, characterization, and imaging of radiopaque bismuth beads for image-guided transarterial embolization. Scientific Reports, 11, 533.

Publication 2021

Progreat Renegade Omnipaque 350

Bismuth Catheter Dilution Homogenous Iohexol Omnipaque

Corresponding Organization : National Institutes of Health Clinical Center

Other organizations : Biocompatibles (United Kingdom), National Institute of Neurological Disorders and Stroke, National Institutes of Health, National Cancer Institute, University Medical Center Utrecht, University of Twente, Center for Cancer Research

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Variable analysis

independent variables

Catheter size (2.0-Fr Progreat and 2.4 Fr Renegade)

dependent variables

Catheter clogging (recorded as a failure)

control variables

Bead suspension in 100% iohexol (Omnipaque 350) as a 1:10 bead dilution
1- or 3-mL syringes used for administration
Catheter laid on a bench with a 10 cm diameter coil mid-catheter to introduce curvature in the flow path

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