Digitalization and Image Analysis

Prior to image analysis, slides were digitalized using the NanoZoomer-Series Digital slide scanner (Hamamatsu Photonics). Digital image analysis was performed using the HALO^® platform from Indica Labs with the CytoNuclear v1.4 module as described previously (26 (link)).

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Radspieler M.M., Schindeldecker M., Stenzel P., Försch S., Tagscherer K.E., Herpel E., Hohenfellner M., Hatiboglu G., Roth W, & Macher-Goeppinger S. (2019). Lamin-B1 is a senescence-associated biomarker in clear-cell renal cell carcinoma. Oncology Letters, 18(3), 2654-2660.

Publication 2019

NanoZoomer-Series Digital slide scanner

Corresponding Organization :

Other organizations : University Medical Center of the Johannes Gutenberg University Mainz, Johannes Gutenberg University Mainz, University Hospital Heidelberg

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Variable analysis

independent variables

None explicitly mentioned

dependent variables

Outcomes measured using the HALO® platform from Indica Labs with the CytoNuclear v1.4 module

control variables

None explicitly mentioned

controls

Positive control: Not specified
Negative control: Not specified

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