Structural MRI Processing and Hippocampal Volume

MRI scans were obtained on a Sonata 1.5T, Vision 1.5T, or Trio 3.0T scanner (Siemens Corporation). Structural MRI processing steps have been described in detail previously (Buckner et al., 2004 (link); Xiong et al, 2011 (link)) and included motion correction, averaging across scans, atlas transformation, and inhomogeneity correction. Regional volumes were obtained via the Freesurfer image analysis suite (Version 4.1.0, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts). Hippocampal volume was selected as the region of interest (ROI) in this analysis and corrected for total brain volume.

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Duchek J.M., Aschenbrenner A.J., Fagan A.M., Benzinger T.L., Morris J.C, & Balota D.A. (2019). The Relation Between Personality and Biomarkers in Sensitivity and Conversion to Alzheimer Type Dementia. Journal of the International Neuropsychological Society : JINS, 26(6), 596-606.

Publication 2019

Sonata 1.5T Vision 1.5T Trio 3.0T scanner

Brain Mri scans Scans Sonata Trio Vision

Corresponding Organization : Washington University in St. Louis

Other organizations : Neurological Surgery

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Variable analysis

independent variables

MRI scanner type (Sonata 1.5T, Vision 1.5T, or Trio 3.0T scanner)

dependent variables

Hippocampal volume (corrected for total brain volume)

control variables

Motion correction
Averaging across scans
Atlas transformation
Inhomogeneity correction

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