CUT&Tag was performed as described previously [40 (link),82 (link)] using the CUT&Tag-IT Assay Kit from Active Motif (Catalog No. 53160) and following manufacturer’s instructions. Sequencing was done at the Genomic Sequencing and Analysis Facility of The University of Texas at Austin or the MD Anderson Cancer Center-Science Park NGS Facility using Illumina Novaseq in 2 x 150 or 2 x 75 PE mode.
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