Optimizing iNKT Cell Activation
Corresponding Organization :
Other organizations : Immune Regulation (United Kingdom), Medical Research Council, University of Birmingham, Inserm, Aix-Marseille Université, Centre de Recherche en Cancérologie de Marseille, Centre d’Immunologie de Marseille-Luminy
Variable analysis
- Presence or absence of Ccr7 gene (WT and Ccr7^-/- mice)
- Thymic iNKT cell populations
- Dose of injected soluble IL-15/IL-15Rα complexes (2.5 mg rIL-15 and 15 mg IL-15Rα in 300 μl PBS)
- Route of injection (i.p.)
- Timepoint of analysis (4 days post-injection)
- Positive control: WT mice
- Negative control: Ccr7^-/- mice
Annotations
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