Study design
A cross-sectional study using non-probability consecutive sampling was conducted between January 2021 and September 2022 at the Chughtai Institute of Pathology with Institutional Review Board approval (CIP/IRB/1123). It is one of the largest private laboratories in Pakistan that accepts samples from all over the country. Chughtai Laboratories operate in multiple locations throughout the country. Because of its geographical location in the middle of the second largest city in Pakistan, approximately 70% of the total number of patients attending this clinic are residents of different areas of Pakistan.
Inclusion criteria
According to the World Health Organization (WHO) Classification of Tumors of Hematopoietic and Lymphoid Tissues, all diagnosed cases of B-cell NHL were included in the study. In this study, individuals of both genders, regardless of their age, were included.
Exclusion criteria
The study excluded biopsies with poor preservation, tru-cut biopsies that were inconclusive for diagnosis, unclassifiable lymphomas, cytological specimens, as well as bone marrow biopsies.
Data collection
The data for this study were retrieved from the archive of the institute using an electronic data system (Nexus Pro). Data regarding patient age, gender, location of involvement, and subtypes of B-cell NHL were also documented. The specific subtypes of the tumor were accompanied by specific information regarding the type of tumor, its location, and whether it had been described as a nodal or extra-nodal variant.
Statistical analysis
Statistical Package for the Social Sciences (SPSS) version 26.0 (IBM Corp., Armonk, NY, USA) was used to analyze the data. Qualitative variables were presented as frequencies and percentages. Quantitative variables were presented as mean and standard deviation. A chi-square test was applied, and a p-value of less than 0.05 was considered statistically significant.
A cross-sectional study using non-probability consecutive sampling was conducted between January 2021 and September 2022 at the Chughtai Institute of Pathology with Institutional Review Board approval (CIP/IRB/1123). It is one of the largest private laboratories in Pakistan that accepts samples from all over the country. Chughtai Laboratories operate in multiple locations throughout the country. Because of its geographical location in the middle of the second largest city in Pakistan, approximately 70% of the total number of patients attending this clinic are residents of different areas of Pakistan.
Inclusion criteria
According to the World Health Organization (WHO) Classification of Tumors of Hematopoietic and Lymphoid Tissues, all diagnosed cases of B-cell NHL were included in the study. In this study, individuals of both genders, regardless of their age, were included.
Exclusion criteria
The study excluded biopsies with poor preservation, tru-cut biopsies that were inconclusive for diagnosis, unclassifiable lymphomas, cytological specimens, as well as bone marrow biopsies.
Data collection
The data for this study were retrieved from the archive of the institute using an electronic data system (Nexus Pro). Data regarding patient age, gender, location of involvement, and subtypes of B-cell NHL were also documented. The specific subtypes of the tumor were accompanied by specific information regarding the type of tumor, its location, and whether it had been described as a nodal or extra-nodal variant.
Statistical analysis
Statistical Package for the Social Sciences (SPSS) version 26.0 (IBM Corp., Armonk, NY, USA) was used to analyze the data. Qualitative variables were presented as frequencies and percentages. Quantitative variables were presented as mean and standard deviation. A chi-square test was applied, and a p-value of less than 0.05 was considered statistically significant.
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