The SLR was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2009 guidelines (Supplementary Table 1 ) [28 (link)]. The SLR protocol was registered in the PROSPERO database [29 ].
Relevant articles in English (with no limit on the date of publication) were identified via online searches of the Embase®, MEDLINE®, and PubMed® databases conducted on March 16, 2020, and subsequently updated on March 16, 2021. Relevant abstracts were also identified via online searches of congress websites and abstract supplements covering the most recent meetings (at the time of the search) of the ACR, Childhood Arthritis and Rheumatology Research Alliance, European League Against Rheumatism, and Paediatric Rheumatology European Society.
The searches applied population, intervention, comparator, outcomes, and study types criteria to identify relevant publications (Supplementary Table2 ). The search strategies used for each of the online databases are shown in Supplementary Tables 3 –5 . In addition to online searches, the reference lists of relevant review articles and all publications included in the SLR were also searched by an analyst (C. Rolland) to identify any publications not indexed by the online databases.
Relevant articles in English (with no limit on the date of publication) were identified via online searches of the Embase®, MEDLINE®, and PubMed® databases conducted on March 16, 2020, and subsequently updated on March 16, 2021. Relevant abstracts were also identified via online searches of congress websites and abstract supplements covering the most recent meetings (at the time of the search) of the ACR, Childhood Arthritis and Rheumatology Research Alliance, European League Against Rheumatism, and Paediatric Rheumatology European Society.
The searches applied population, intervention, comparator, outcomes, and study types criteria to identify relevant publications (Supplementary Table
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