Na2CO3, NaCl, and 20% HCl were obtained from Fluka, while 4-nitrobenzene sulfonyl chloride and 4-hydroxyproline were obtained from Sigma Aldrich (Bristol Scientific Nigeria). IR spectra were recorded on Bruker FT-IR spectrophotometer. The NMR peaks were recorded on Bruker DPX 300 spectrophotometer with 1H at 400 MHz and 13 ℃ at 100 MHz. Chemical shifts δ are given in ppm and referenced to tetramethylsilane. Methanol was used as a solvent for crystallization. X-ray data of the single crystal were collected on an XtaLAB Synergy, Dualflex, Pilatus 200 K diffractometer using CuKα radiation at 105.4 (7)K. The pharmacokinetic properties were studied using SwissADME free online tool (https://www.swissadme.ch), while the Molecular docking was carried out using the Molecular operating environment (MOE) (AutoDock Vina, BIOVIA).