Florbetapir-PET Imaging Protocol

All Florbetapir-PET scans were acquired in a single session on a Philips Gemini GXL CT-PET scanner 50 (± 5) min after injection of approximately 370 MBq (333–407 MBq) of Florbetapir. Images acquisition, reconstruction including correction algorithms and reallination, averaging, and quality check were performed by the CATI team (Centre d’Acquisition et Traitement des Images) (http://cati-neuroimaging.com) [19 (link), 24 (link), 25 (link)] and were calculated for each of 12 cortical regions of interest (right and left posterior cingulate, right and left anterior cingulate, right and left superior frontal, right and left inferior parietal, right and left precuneus, right and left middle temporal cortices), as well as the global average standard uptake value ratio (SUVR).

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Baldacci F., Lista S., Manca M.L., Chiesa P.A., Cavedo E., Lemercier P., Zetterberg H., Blennow K., Habert M.O., Potier M.C., Dubois B., Vergallo A, & Hampel H. (2020). Age and sex impact plasma NFL and t-Tau trajectories in individuals with subjective memory complaints: a 3-year follow-up study. Alzheimer's Research & Therapy, 12, 147.

Publication 2020

Gemini GXL CT-PET scanner

Anterior cingulate Cortical Ct pet Florbetapir Pet scans Posterior cingulate Precuneus Reconstruction Temporal cortices

Corresponding Organization :

Other organizations : Alzheimer Precision Medicine, Assistance Publique – Hôpitaux de Paris, University of Pisa, Sorbonne Université, Pitié-Salpêtrière Hospital, Institut du Cerveau, University of Gothenburg, University College London, UK Dementia Research Institute, Laboratoire d’Imagerie Biomédicale

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Variable analysis

independent variables

Independent variables not explicitly mentioned.

dependent variables

Standard uptake value ratio (SUVR) for each of 12 cortical regions of interest (right and left posterior cingulate, right and left anterior cingulate, right and left superior frontal, right and left inferior parietal, right and left precuneus, right and left middle temporal cortices)
Global average standard uptake value ratio (SUVR)

control variables

Florbetapir-PET scans were acquired in a single session on a Philips Gemini GXL CT-PET scanner
Scans were performed 50 (± 5) min after injection of approximately 370 MBq (333–407 MBq) of Florbetapir
Image acquisition, reconstruction including correction algorithms and reallination, averaging, and quality check were performed by the CATI team

positive controls

None mentioned.

negative controls

None mentioned.

Annotations

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