Standardized Multimodal MRI Protocol

MRI scanning was performed on a 1.5T Magnetom scanner (Siemens, Erlangen, Germany). The scanning protocol included whole-brain 3D T1 magnetization-prepared rapid gradient echo sequence (repetition time [TR]/echo time [TE]/inversion time [TI] 2,730/2.95/1,000 ms; flip angle 7°; voxel size 1.0 × 1.0 × 1.0 mm); fluid-attenuated inversion recovery (FLAIR) pulse sequences (TR/TE/TI 12,220/85/2,200 ms; voxel size 1.0 × 1.2 × 3.0; slice gap 0.6 mm); transversal T2-weigted turbo spin echo sequence (TR/TE 7,440/96 ms; voxel size 0.9/0.9 × 3.0 mm; slice gap 0.6 mm); and gradient echo susceptibility-weighted imaging (SWI) sequence (TR/TE 49/40 ms; voxel size 0.8 × 0.7 × 1.0 mm). All patients underwent MRI scanning according to this standardized protocol.^{8 (link)}