Aniline Synthesis via Nitrobenzene Reduction

The Au-NC/SCNPs were used as catalysts for the reduction at r.t. of nitrobenzene (0.2 mmol) to aniline in the presence of NaBH₄ (0.8 mmol). The same procedure described in Section 2.3.3 was followed. Absorbance was recorded by taking 2 µL of crude at a given reaction time, which was then diluted in 4 mL of deionized water. After reaction, aniline was purified via preparative TLC (n-hexane/ethyl acetate 1:1), with a yield of 96%. ¹H NMR (400 MHz, DMSO-d₆, ppm): δ 3.65 (s, 2H), 6.67–6.70 (m, 2H), 6.73–6.77 (m, 1H), 7.13–7.17 (m, 2H).

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Pinacho-Olaciregui J., Verde-Sesto E., Taton D, & Pomposo J.A. (2024). Gold Nanoclusters Synthesized within Single-Chain Nanoparticles as Catalytic Nanoreactors in Water. Polymers, 16(3), 378.

Publication 2024

Corresponding Organization : University of the Basque Country

Other organizations : Laboratoire de Chimie des Polymères Organiques, Institut Polytechnique de Bordeaux, Université de Bordeaux

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Variable analysis

independent variables

Au-NC/SCNPs (used as catalysts)

dependent variables

Reduction of nitrobenzene (0.2 mmol) to aniline
Aniline yield (96%)

control variables

Presence of NaBH4 (0.8 mmol)
Reaction temperature (room temperature)

controls

The same procedure described in Section 2.3.3 was followed.

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