General Anesthesia for Preventing PONV

Both groups were treated with tracheal intubation general anesthesia, propofol 2 mg/kg + cisatracurium 0.15 mg/kg + sufentanil 0.4 μg/kg induction, and all patients received propofol, remifentanil, and sevoflurane as intraoperative maintenance drugs. Propofol was maintained at 2.5–5 mg/kg; remifentanil was maintained at 5–10 μg/kg during the operation, according to the patient’s blood pressure and BIS value (aimed for 40–60); an experimental anesthesiologist controlled the dose and recorded the total dose. Because inhaled anesthetics are a risk factor for PONV, we set the MAC of two groups of sevoflurane to 0.3, and the concentration was less than 1%. If the operation lasted more than one hour, we regularly added atracurium 0.03 mg/kg and sufentanil 5 μg per hour. Neostigmine was administered intravenously to reverse the residual effect of the muscle relaxant when the train-of-four (TOF) ratio was less than 0.9 after the operation at 0.05 mg/kg. Before the end of the surgery, all patients were given flurbiprofen axetil 50 mg intravenously for analgesia.