Example 2

In the current invention, we have synthesized sugar and deoxy sugar-modified amphiphilic dendrimer hybrids. These amphiphilic molecules have hydrophobic units, thus should be able to self-assemble in solution whereas the hydrophilic sugar moieties should improve biocompatibility and loading capacity of the nucleic acid carrier.

[Figure (not displayed)]
where A is an amine linker, B is a hydrophobic unit, Y is a sugar moiety and Z is a deoxy sugar moiety

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