Whole-cell MALDI-TOF MS was conducted as reported previously [23] (link). Briefly, cell samples were dissolved in a α-cyano-4-hydroxy-cynnamique acid (CHCA) or 2, 5-dihydroxybenzoic acid (DHB) matrix and then dried on a MALDI target. The fingerprint was detected and analyzed using an Autoflex III mass spectrometer and FlexAnalysis software (Bruker Daltonics, Bremen, Germany).
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