4-Methylumbelliferyl heptanoate (MUH) assays were performed as previously described22 (link). The cells were treated with cisplatin (Hexal, up to 20 µM), carboplatin (Medac, up to 250 µM), vemurafenib (LC Laboratories, up to 20 µM), trametinib (Selleck Chemicals, up to 250 nM), 5-fluorouracil (R&D Systems, up to 25 µM), paclitaxel (Merck, up to 500 nM) or temozolomide (TMZ; Merck, up to 50 µM) for 72 h.
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