Patients with confirmed histopathological reports of IDC (30) and ILC (28) from the Duke breast cancer MRI data set of the cancer imaging archive (TCIA) were included in this study
18
,19 (link)
(underlying data).
20 (link)
Sample size for the study was calculated using the formula of sensitivity and specificity for diagnostic test accuracy based on sensitivity and specificity and area under the curve.
The MRI breast dataset (IDC and ILC) used for this study is publicly available online at
https://wiki.cancerimagingarchive.net/;
https://doi.org/10.7937/TCIA.e3sv-re93). The Duke breast cancer dataset is composed of a retrospectively collected cohort of 922 biopsy-confirmed invasive breast cancer patients from a single institution (Duke Hospital, Durham, North Carolina, USA) with preoperative MRI from January 1, 2000 to March 23, 2014. The images were acquired using 1.5 Tesla GE (
Signa Excite,
Signa HDxt) and Siemens (Avanto) MRI scanners. The mean age (years) of the patients with IDC and ILC was 48 ± 11.15 and 59 ± 11 years, respectively. Demographic characteristics are shown in
Table 1. Axial T1 dynamic post-contrast (DCE) sequence (gadolinium-based contrast of 15–20 ml) was performed using the image acquisition parameters listed in
Table 2.