Femur Microstructure Characterization by μ-CT

The right femurs were subjected to the μ-CT scanning as previously described [36 (link),37 (link)]. Briefly, the right femur was scanned and captured by the Quantum GX μCT instrument (PerkinElmer, Waltham, MA, USA). The parameters in the volume of interest were analyzed by the Analyzer Software (V12.0), including (1) BMD (bone mineral density); (2) BV/TV (bone volume fraction); (3) BS/TV (bone surface density); (4) Tb.N (trabecular number); (5) Tb.Sp (trabecular separation); (6) Tb.Th (trabecular thickness); (7) Conn.D (connectivity density); and (8) SMI (Structure Model Index).

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Xia B., Dai X., Shi H., Yin J., Xu T., Liu T., Yue G., Guo H., Liang R., Liu Y., Gao J., Wang X., Chen X., Tang J., Wang L., Zhu R, & Zhang D. (2024). Lycopene Promotes Osteogenesis and Reduces Adipogenesis through Regulating FoxO1/PPARγ Signaling in Ovariectomized Rats and Bone Marrow Mesenchymal Stem Cells. Nutrients, 16(10), 1443.

Publication 2024

Quantum GX μCT

Corresponding Organization : Chinese Academy of Medical Sciences & Peking Union Medical College

Other organizations : Xuchang University, First Affiliated Hospital of Henan University

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Variable analysis

independent variables

None explicitly mentioned

dependent variables

BMD (bone mineral density)
BV/TV (bone volume fraction)
BS/TV (bone surface density)
Tb.N (trabecular number)
Tb.Sp (trabecular separation)
Tb.Th (trabecular thickness)
Conn.D (connectivity density)
SMI (Structure Model Index)

control variables

None explicitly mentioned

controls

Positive control: None mentioned
Negative control: None mentioned

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