A total of 14 4-week-old healthy male Wister rats were used in this experiment. 300TCP and 500TCP were transplanted into rat femoral muscles. To investigate the optimal structure of honeycomb TCP for bone marrow formation, the animals were randomly divided into 2 groups: 300TCP loaded with BMP-2 diluted to a final contained amount of 1000 ng in Matrigel® and 500TCP loaded with BMP-2 diluted to a final contained amount of 1000 ng in Matrigel®.
All experiments were performed in accordance with Okayama University’s Policy on the Care and Use of the Laboratory Animals and approved by the Animal Care and Use Committee. All surgical procedures were performed under general anesthesia in a pain-free state.
All experiments were performed in accordance with Okayama University’s Policy on the Care and Use of the Laboratory Animals and approved by the Animal Care and Use Committee. All surgical procedures were performed under general anesthesia in a pain-free state.
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