Cocaine hydrochloride and BD1047 dihydrobromide (a highly selective putative Sig1R antagonist) were purchased from Sigma Aldrich (St. Louis, MO.), PRE-084 (2-(4-Morpholinethyl)-1 phenylcyclohexanecarboxylate hydrochloride) at 99.9% purity was obtained from Tocris Pharmaceuticals (Avonmouth, Bristol, UK). The cocaine dose selected for this study (10 μM) was based on our previous studies and other viability assays (Zenón et al. 2014 (link)).
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