Sprague Dawley Rat Edema Study

Female Sprague Dawley (SD) rats were purchased from Charles River Laboratories. Animals were maintained under a 12-h light/dark cycle and were provided food and water ad libitum. All rats were 8–10 weeks of age at the time of experimentation. A group size of three was used for each time point for the edema progression study and five animals were used for each case in the treatment study. The sample size of the animals is calculated in terms of a resource equation (Kilkenny et al., 2009 (link)).

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Hale C., Yonan J., Batarseh R., Chaar R., Jonak C.R., Ge S., Binder D, & Rodgers V.G. (2020). Implantable Osmotic Transport Device Can Reduce Edema After Severe Contusion Spinal Cord Injury. Frontiers in Bioengineering and Biotechnology, 8, 806.

Publication 2020

Female Sprague Dawley (SD) rats

Animals Edema Female Food Progression Rats River Sprague dawley rats

Corresponding Organization : University of California, Riverside

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Variable analysis

independent variables

Treatment

dependent variables

Edema progression

control variables

Female Sprague Dawley (SD) rats
12-h light/dark cycle
Food and water provided ad libitum
Animals aged 8–10 weeks

controls

A group size of three was used for each time point for the edema progression study
Five animals were used for each case in the treatment study
The sample size of the animals is calculated in terms of a resource equation (Kilkenny et al., 2009)

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