Sciatic-nerve transection and ligation was performed as previously described9 (link). LPS (E. coli O127:B8, Sigma) was administered as a single 2.5 mg/kg intraperitoneal dose. Tamoxifen (Sigma) was injected as 100 mg/kg per animal for five consecutive days for recombination. All the experiments were performed 7 days after the first dose of Tamoxifen injection.
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