Antivirals and HIV Plasmid Protocol

The antivirals Emtricitabine (FTC), Tenofovir Disoproxil Fumarate (TDF), Raltegravir (RAL), abacavir (ABC), dolutegravir (DOL), lamivudine (3TC), tenofovir alafenamide (TAF) were a gift from Gilead Sciences or were obtained from pharmacy. HIV p89.6 plasmid DNA was obtained from the NIH AIDS reagent Program. Murine chow diet with antibiotic was purchased from Envigo Teklad Diets. All other materials were purchased from commercially available sources and have been previously described in detail [15 (link)]. All lipids were purchased from Cayman Chemicals (Ann Arbor, MI, USA) and are described in detail in the Supplemental material.

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Daskou M., Sharma M., Mu W., Heymans R., Ritou E., Rezek V., Hamid P., Kossyvakis A., Sen Roy S., Grijalva V., Chattopadhyay A., Papesh J., Meriwether D., Kitchen S.G., Fogelman A.M., Reddy S.T, & Kelesidis T. (2021). ApoA-I mimetics favorably impact cyclooxygenase 2 and bioactive lipids that may contribute to cardiometabolic syndrome in chronic treated HIV. Metabolism: clinical and experimental, 124, 154888.

Publication 2021

Emtricitabine Tenofovir Disoproxil Fumarate Raltegravir abacavir dolutegravir lamivudine tenofovir alafenamide

Abacavir Aids Antibiotic Antivirals Cayman Diet Diets Dolutegravir Lipids Murine Plasmid Raltegravir Tenofovir alafenamide Tenofovir disoproxil fumarate

Corresponding Organization : University of California, Los Angeles

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Variable analysis

independent variables

Emtricitabine (FTC)
Tenofovir Disoproxil Fumarate (TDF)
Raltegravir (RAL)
Abacavir (ABC)
Dolutegravir (DOL)
Lamivudine (3TC)
Tenofovir alafenamide (TAF)

dependent variables

Not explicitly mentioned

control variables

Murine chow diet with antibiotic purchased from Envigo Teklad Diets
All other materials purchased from commercially available sources and have been previously described in detail [15 (link)]
All lipids purchased from Cayman Chemicals (Ann Arbor, MI, USA) and described in detail in the Supplemental material

positive controls

Not explicitly mentioned

negative controls

Not explicitly mentioned

Annotations

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