Controlled Ovarian Hyperstimulation Protocol

Women underwent controlled ovarian hyperstimulation with a GnRH short antagonist (cetrorelix; Merck Serono, Geneve, Switzerland; ganirelix; Organon, Oss, the Netherlands) protocol in the majority of the cases. For stimulation, rFSH was mainly used (Puregon; Organon; Gonal-F; Merck Serono, Germany). About 36 h before oocyte recovery, HCG was administered (Pregnyl; Organon). Estradiol serum levels were assayed at the day of HCG or 1 day before.28 (link)29 (link)

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Gonçalves C., Cunha M., Rocha E., Fernandes S., Silva J., Ferraz L., Oliveira C., Barros A, & Sousa M. (2016). Y-chromosome microdeletions in nonobstructive azoospermia and severe oligozoospermia. Asian Journal of Andrology, 19(3), 338-345.

Publication 2016

cetrorelix ganirelix Puregon Gonal-F Pregnyl

Cetrorelix Estradiol Ganirelix Gnrh Gonal f Oocyte recovery Ovarian hyperstimulation Pregnyl Puregon Serum Women

Corresponding Organization : Universidade do Porto

Other organizations : University of Aveiro, Centro de Genética Clínica, i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Centro Hospitalar de Vila Nova de Gaia

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Variable analysis

independent variables

Controlled ovarian hyperstimulation protocol
GnRH short antagonist (cetrorelix; Merck Serono, Geneve, Switzerland; ganirelix; Organon, Oss, the Netherlands)
Recombinant follicle-stimulating hormone (rFSH) (Puregon; Organon; Gonal-F; Merck Serono, Germany)

dependent variables

Estradiol serum levels

control variables

Time of estradiol serum level measurement (day of HCG or 1 day before)

controls

Positive control: Not specified
Negative control: Not specified

Annotations

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