Synthesis of Disubstituted Triazine Derivative

A mixture of disubstituted triazine 10 (3 mmol) and dimethylamine (3 mmol) in dioxane (15 mL) was stirred at room temperature for 1 h. The mixture was poured onto crushed ice, filtered, and washed with water.

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Moreno L.M., Quiroga J., Abonia R., Crespo M.D., Aranaga C., Martínez-Martínez L., Sortino M., Barreto M., Burbano M.E, & Insuasty B. (2024). Synthesis of Novel Triazine-Based Chalcones and 8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepines as Potential Leads in the Search of Anticancer, Antibacterial and Antifungal Agents. International Journal of Molecular Sciences, 25(7), 3623.

Publication 2024

Corresponding Organization : Universidad del Valle

Other organizations : Universidad Santiago de Cali, University of Córdoba, Instituto Maimónides de Investigación Biomédica de Córdoba, Hospital Universitario Reina Sofía, National University of Rosario

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Variable analysis

independent variables

Mixture of disubstituted triazine 10 (3 mmol)
Dimethylamine (3 mmol)

dependent variables

Not explicitly mentioned

control variables

Reaction solvent (dioxane, 15 mL)
Reaction temperature (room temperature)
Reaction time (1 h)

controls

No positive or negative controls were explicitly mentioned

Annotations

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